Reactive species
Human; Mouse;Rat
Antibody type
Polyclonal Antibody
Gene Name
MICAL1 MICAL NICAL
Immunogen
Synthesized peptide derived from human MICA1 AA range: 155-205
Specificity
This antibody detects endogenous levels of MICA1 at Human/Mouse/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes an enzyme that oxidizes methionine residues on actin, thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed, developmentally down-regulated 9). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],
Function
cofactor:FAD .,domain:The C-terminal coiled coil part contains the plexin-interacting region.,function:May be a cytoskeletal regulator that connects NEDD9 to intermediate filaments.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 LIM zinc-binding domain.,subunit:Associates with the SH3 domain of NEDD9. Interacts with VIM and PLXNA3. Interacts with RAB1B.,tissue specificity:Expressed in the thymus, lung, spleen, kidney, testis and hematopoietic cells.,
