Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
ZNF473 KIAA1141 ZFP100
Immunogen
Synthesized peptide derived from human ZN473 AA range: 279-329
Specificity
This antibody detects endogenous levels of ZN473 at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein, a component of the U7 snRNP complex, plays a role in histone 3'-end pre-mRNA processing and may be required for cell cycle progression to S phase. Expression level and methylation status of this gene may be correlated with bone mineral density. [provided by RefSeq, Jul 2016],
Function
function:Involved in histone pre-mRNA processing, most likely by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 20 C2H2-type zinc fingers.,subunit:Interacts with the SLBP/pre-mRNA complex but not with SLBP alone.,