Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
Beta-defensin 1
Immunogen
Synthesized peptide derived from human Beta-defensin 1 AA range: 1-50
Specificity
This antibody detects endogenous levels of human Beta-defensin 1
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Purification process
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Other name
Beta-defensin 1 (BD-1;hBD-1;Defensin, beta 1)
Background
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008],
Function
function:Has bactericidal activity.,mass spectrometry: PubMed:7628632,similarity:Belongs to the beta-defensin family.,tissue specificity:Plasma.,