Reactive species
Human;Rat
Applications
WB;IHC;IF;ELISA
Antibody type
Polyclonal Antibody
Protein name
Interleukin-19 (IL-19) (Melanoma differentiation-associated protein-like protein) (NG.1)
Immunogen
Synthetic peptide from human protein at AA range: 51-100
Specificity
The antibody detects endogenous IL-19
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000. IF 1:50-200
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
Interleukin-19 (IL-19;Melanoma differentiation-associated protein-like protein;NG.1)
Background
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008],
Function
function:May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis.,similarity:Belongs to the IL-10 family.,
