Reactive species
Human; Mouse;Rat
Antibody type
Polyclonal Antibody
Protein name
USP28 (Phospho-Ser714)
Immunogen
Synthesized peptide derived from human USP28 (Phospho-Ser714)
Specificity
This antibody detects endogenous levels of USP28 (Phospho-Ser714) at Human, Mouse,Rat
Constitute
Liquid in PBS containing 50% glycerol, and 0.182% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Other name
Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)
Background
The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. [provided by RefSeq, Oct 2016],
Function
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UIM (ubiquitin-interacting motif) repeat.,
