Reactive species
Human;Mouse
Applications
WB;ELISA;IHC
Antibody type
Polyclonal Antibody
Gene Name
SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL
Protein name
Scribble (Ser1220)
Immunogen
Synthesized phosho peptide around human Scribble (Ser1220)
Specificity
This antibody detects endogenous levels of Human Mouse Scribble (phospho-Ser1220)
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Other name
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Background
This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
Function
similarity:Contains 4 PDZ (DHR) domains.,
