Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
RCC1 (Ser11)
Immunogen
Synthesized phosho peptide around human RCC1 (Ser11)
Specificity
This antibody detects endogenous levels of Human RCC1 (phospho-Ser11)
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Other name
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)
Function
disease:Patients with Raynaud disease produce antibodies that bind to RCC1.,function:Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds to the chromatin. RCC1/Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA.,similarity:Contains 7 RCC1 repeats.,subcellular location:Becomes dispersed throughout the cytoplasm during mitosis.,
