Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Gene Name
KRTAP5-9 KAP5.9 KRN1 KRTAP5.9 UHSK1
Immunogen
Synthesized peptide derived from human KRA59 AA range: 9-59
Specificity
This antibody detects endogenous levels of KRA59 at Human
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
developmental stage:At a late stage of fiber differentiation.,function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 5 family.,subunit:Interacts with hair keratins.,tissue specificity:Restricted to hair root, not detected in any other tissues. Expressed in cuticle layers of differentiating hair follicles.,
