Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Immunogen
Synthesized peptide derived from human TSSP AA range: 50-100
Specificity
This antibody detects endogenous levels of TSSP at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008],
Function
developmental stage:Expressed in fetal thymus.,function:Protease that may play a role in T-cell development.,similarity:Belongs to the peptidase S28 family.,subcellular location:Vesicular, either lysosomal or endosomal.,tissue specificity:Expressed predominantly in cortical thymic epithelial cells.,
