Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
GMCL1P1 GCL GMCL1L
Immunogen
Synthesized peptide derived from human GMCLL AA range: 20-70
Specificity
This antibody detects endogenous levels of GMCLL at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This locus shares a high degree of identity with the multi-exon germ cell-less gene on chromosome 2. Despite its single-exon nature, this chromosome 5 locus contains an open reading frame that could putatively encode a full-length germ cell-less related protein. [provided by RefSeq, Jul 2008],
Function
function:Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity). Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,function:Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 BTB (POZ) domain.,subunit:Interacts with TMPO-beta, TSG101 and TFDP2 (By similarity). Interacts with EMD.,subunit:Interacts with TMPO-Beta, TSG101 and TFDP2. Interacts with EMD (By similarity). Interacts with CUL3.,
