Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
SETBP1 KIAA0437
Immunogen
Synthesized peptide derived from human SETBP AA range: 990-1040
Specificity
This antibody detects endogenous levels of SETBP at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],
Function
similarity:Contains 3 A.T hook DNA-binding domains.,subunit:Interacts with SET.,tissue specificity:Expressed in numerous tissues.,
