Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
TRAIP RNF206 TRIP
Immunogen
Synthesized peptide derived from human TRAIP AA range: 399-449
Specificity
This antibody detects endogenous levels of TRAIP at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008],
Function
function:Inhibits activation of NF-kappa-B mediated by TNF.,similarity:Contains 1 RING-type zinc finger.,subunit:Binds TRAF1 and TRAF2 and is part of the receptor-TRAF signaling complex (By similarity). Interacts with CYLD.,
