Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
SEPHS1 SELD SPS SPS1
Immunogen
Synthesized peptide derived from human SPS1 AA range: 323-373
Specificity
This antibody detects endogenous levels of SPS1 at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. [provided by RefSeq, Sep 2010],
Function
catalytic activity:ATP + selenide + H(2)O = AMP + selenophosphate + phosphate.,caution:The conserved active site Cys (or selenocysteine) residue in position 29 is replaced by a Thr. However, as function in selenoprotein synthesis is proven, it is possible Cys-31 is the active site.,function:Synthesizes selenophosphate from selenide and ATP.,similarity:Belongs to the selenophosphate synthetase 1 family. Class II subfamily.,