Reactive species
Human;Rat
Antibody type
Polyclonal Antibody
Immunogen
Synthesized peptide derived from human KCNT2 AA range: 689-739
Specificity
This antibody detects endogenous levels of KCNT2 at Human/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1.,PTM:Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain inhibits channel activity.,similarity:Belongs to the potassium channel family. Calcium-activated subfamily.,similarity:Contains 1 RCK N-terminal domain.,
