Background
This gene encodes a tumor antigen recognized by autologous cytolytic lymphocytes (CTL). [provided by RefSeq, Jul 2008],
Function
alternative products:At least 6 different mRNAs, BAGE1a, BAGE1b, BAGE1c, BAGE1d, BAGE1e and BAGE1f, are produced by alternative splicing. They differ in the 3' region, but give rise to the same protein sequence,function:Unknown. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.,miscellaneous:The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21.,similarity:Belongs to the BAGE family.,tissue specificity:Not expressed in normal tissues, except in testis. Expressed with significant proportion in melan
