Reactive species
Human; Mouse;Rat
Antibody type
Polyclonal Antibody
Gene Name
ABTB1 BPOZ PP2259
Immunogen
Synthesized peptide derived from human ABTB1 AA range: 163-213
Specificity
This antibody detects endogenous levels of ABTB1 at Human/Mouse/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010],
Function
function:May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.,similarity:Contains 2 ANK repeats.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart.,
