Reactive species
Human; Mouse;Rat
Antibody type
Polyclonal Antibody
Gene Name
RBBP9 BOG RBBP10
Immunogen
Synthesized peptide derived from human RBBP9 AA range: 108-158
Specificity
This antibody detects endogenous levels of RBBP9 at Human/Mouse/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate. [provided by RefSeq, Jul 2008],
Function
function:May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1.,similarity:Belongs to the RBBP9 family.,tissue specificity:Widely expressed. Expressed at higher levels in tumor tissues than in normal tissues.,