Function
domain:The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.,function:May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the TUB family.,similarity:Contains 1 SOCS box domain.,similarity:Contains 3 WD repeats.,tissue specificity:Expressed mainly in the brain, skeletal muscle, testis and kidney.,
