Reactive species
Human; Mouse;Rat
Antibody type
Polyclonal Antibody
Gene Name
SPECC1L CYTSA KIAA0376
Immunogen
Synthesized peptide derived from human CYTSA AA range: 150-200
Specificity
This antibody detects endogenous levels of CYTSA at Human/Mouse/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013],
Function
function:Involved in cytokinesis and spindle organization.,similarity:Belongs to the cytospin-A family.,similarity:Contains 1 CH (calponin-homology) domain.,