Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
TXLNG CXorf15 ELRG LSR5
Immunogen
Synthesized peptide derived from human TXLNG AA range: 219-269
Specificity
This antibody detects endogenous levels of TXLNG at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],
Function
function:May be involved in intracellular vesicle traffic.,similarity:Belongs to the taxilin family.,subunit:Binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A and STX4A.,tissue specificity:Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. Expressed in brain, placenta, lung, liver, kidney and pancreas.,