Reactive species
Human; Mouse;Rat
Antibody type
Polyclonal Antibody
Immunogen
Synthesized peptide derived from human NAB1 AA range: 43-93
Specificity
This antibody detects endogenous levels of NAB1 at Human/Mouse/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
domain:The NAB conserved domain 1 (NCD1) interacts with EGR1 inhibitory domain and mediates multimerization.,domain:The NAB conserved domain 2 (NCD2) is necessary for transcriptional repression.,function:Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2.,similarity:Belongs to the NAB family.,subunit:Homomultimers may associate with EGR1 bound to DNA.,tissue specificity:The short isoform is found in a myeloid Leukemia cell line.,
