Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Immunogen
Synthesized peptide derived from human TXD11 AA range: 110-160
Specificity
This antibody detects endogenous levels of TXD11 at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.,sequence caution:Intron retention.,similarity:Belongs to the protein disulfide isomerase family.,similarity:Contains 2 thioredoxin domains.,subunit:Interacts with the cytoplasmic part of DUOX1 and DUOX2. Interacts with TPO and CYBA.,tissue specificity:Widely expressed at low level. Expressed at higher level in thyroid and prostate.,