Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Gene Name
DEFB118 C20orf63 DEFB18 ESC42
Immunogen
Synthesized peptide derived from human DB118 AA range: 38-88
Specificity
This antibody detects endogenous levels of DB118 at Human
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity against E. coli. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. [provided by RefSeq, Nov 2014],
Function
function:Has antibacterial activity .,similarity:Belongs to the beta-defensin family.,tissue specificity:High-level and epididymis-specific expression. Most abundant in the epithelium of the caput and is also present in the lumen and bound to sperm. Expressed also in pancreas.,
