Reactive species
Human; Mouse;Rat
Antibody type
Polyclonal Antibody
Gene Name
CNNM4 ACDP4 KIAA1592
Immunogen
Synthesized peptide derived from human CNNM4 AA range: 18-68
Specificity
This antibody detects endogenous levels of CNNM4 at Human/Mouse/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.358% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Other name
Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4)
Background
This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play a role in metal ion transport. Mutations in this gene are associated with Jalili syndrome which consists of cone-rod dystrophy and amelogenesis imperfecta. [provided by RefSeq, Feb 2010],
Function
function:Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions.,miscellaneous:Shares weak sequence similarity with the cyclin family, explaining its name. However it has no cyclin-like function in vivo.,similarity:Belongs to the ACDP family.,similarity:Contains 2 CBS domains.,subunit:Interacts with COX11.,tissue specificity:Widely expressed. Highly expressed in heart.,
