Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
ZER1 C9orf60 ZYG ZYG11BL
Immunogen
Synthesized peptide derived from human ZER1 AA range: 388-438
Specificity
This antibody detects endogenous levels of ZER1 at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.318% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Other name
Protein zer-1 homolog (Hzyg) (Zyg-11 homolog B-like protein)
Background
This gene encodes a subunit of an E3 ubiquitin ligase complex that may be involved in meiosis. The encoded protein contains three leucine-rich repeat motifs. [provided by RefSeq, Nov 2012],
Function
function:Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZER1-CUL2-Elongin BC.,similarity:Belongs to the zyg-11 family.,similarity:Contains 3 LRR (leucine-rich) repeats.,similarity:Contains 5 ARM repeats.,subunit:Interacts with the TCEB1-TCEB2/Elongin BC complex. Part of an E3 ubiquitin ligase complex including ZER1, CUL2 and Elongin BC.,tissue specificity:Expressed in testis, spermatocytes and spermatides (at protein level). Expressed in spermatocytes, spermatides, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas.,
