Function
function:In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.,similarity:Belongs to the BRAG family.,similarity:Contains 1 IQ domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 SEC7 domain.,subcellular location:At steady state, may be preferentially cytosolic.,subunit:Interacts with ARF6.,tissue specificity:Expressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis.,
