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RRP44 rabbit pAb

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Product code: YP-Ab-08135
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Product introduction

Reactive species
Human; Mouse
Applications
WB
Antibody type
Polyclonal Antibody
Gene Name
DIS3 KIAA1008 RRP44
Protein name
RRP44
Dalton（DA）
105kD
Immunogen
Synthesized peptide derived from human RRP44 AA range: 262-312
Specificity
This antibody detects endogenous levels of RRP44 at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.250% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Stockpile
-20°C/1 year
Other name
Exosome complex exonuclease RRP44 (EC 3.1.13.-) (EC 3.1.26.-) (Protein DIS3 homolog) (Ribosomal RNA-processing protein 44)
Background
Function
function:Component of the exosome 3'->5' exoribonuclease complex. Required for the 3'-processing of the 7S pre-RNA to the mature nuclear complex. Also associated with the GTPase Ran. Has a 3'-5' exonuclease activity.,similarity:Belongs to the ribonuclease II (RNB) family.,similarity:Contains 1 PINc domain.,subunit:Component of the exosome multienzyme ribonuclease complex composed of at least 11 proteins: RRP4, RRP40, RRP41/SKI6, RRP42, RRP43, RRP44/DIS3, PM/Scl-75, RRP46, CSL4 and PM/Scl-100 (only in the nuclear complex). Also associated with the GTPase Ran.,tissue specificity:Widely expressed.,

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