Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
CARS2 OK/SW-cl.10
Immunogen
Synthesized peptide derived from human SYCM AA range: 95-145
Specificity
This antibody detects endogenous levels of SYCM at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.121% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Other name
Probable cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)
Background
This gene encodes a putative member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of cysteine to tRNA molecules. A splice-site mutation in this gene has been associated with a novel progressive myoclonic epilepsy disease with similar symptoms to MERRF syndrome. [provided by RefSeq, Mar 2015],
Function
catalytic activity:ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the class-I aminoacyl-tRNA synthetase family.,
