Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Gene Name
ATXN3L ATX3L MJDL
Immunogen
Synthesized peptide derived from human ATX3L AA range: 99-149
Specificity
This antibody detects endogenous levels of ATX3L at Human
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.64% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Other name
Putative ataxin-3-like protein (EC 3.4.19.12) (Machado-Joseph disease protein 1-like)
Background
This intronless gene may be a pseudogene (PMID:11450850). This gene is similar to the multi-exon gene which encodes ataxin 3 and contains a coding region which could encode a protein similar to ataxin 3. Mutations in the gene encoding ataxin 3 are associated with Machado-Joseph disease. [provided by RefSeq, Sep 2011],
Function
caution:Could be the product of a pseudogene. Suggested by the absence of intron.,function:May bind to histones and regulate transcription. May act as a deubiquitinating enzyme.,similarity:Contains 1 Josephin domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,
