Reactive species
Human; Mouse;Rat
Antibody type
Polyclonal Antibody
Immunogen
Synthesized peptide derived from human PNMA1 AA range: 14-64
Specificity
This antibody detects endogenous levels of PNMA1 at Human/Mouse/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.39% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Other name
Paraneoplastic antigen Ma1 (37 kDa neuronal protein) (Neuron- and testis-specific protein 1)
Background
This gene encodes a neuron- and testis-specific protein that is also expressed in some paraneoplastic syndromes affecting the nervous system. Some patients with neurologic disorders develop antibodies against the protein encoded by this gene. The identification of the antineuronal antibodies in the sera of these patients has facilitated the diagnosis of paraneoplastic neurological disorders and the early detection of the associated tumors. [provided by RefSeq, Feb 2014],
Function
miscellaneous:Antibodies against PNMA1 are present in sera from patients suffering of paraneoplastic neurological disorders.,similarity:Belongs to the PNMA family.,subcellular location:In tumor cells, it is cytoplasmic.,tissue specificity:Testis and brain specific. In some patients suffering from cancers, it is also specifically expressed by the paraneoplastic tumor cells.,