Reactive species
Human;Rat;Mouse;
Immunogen
Synthesized peptide derived from human ZN124 AA range: 190-240
Specificity
This antibody detects endogenous levels of ZN124 at Human
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.14% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Other name
Zinc finger protein 124 (Zinc finger protein HZF-16)
Background
This gene encodes a protein with an amino-terminal KRAB-A box and multiple repeated Kruppel-type (C2H2) zinc finger motifs at its carboxy terminus. The encoded protein may function as a transcription factor. Expression of this gene is increased after vascular endothelial growth factor (VEGF) stimulation in human leukemia cell lines and results in inhibition of apoptotic cell death induced by irradiation or exposure to etoposide. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2014],
Function
function:May be involved in transcriptional regulation.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 8 C2H2-type zinc fingers.,
