Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Gene Name
GPR64 HE6 TM7LN2
Protein name
G-protein coupled receptor 64 (Human epididymis-specific protein 6) (He6)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
GPR64 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],
Function
function:Could be involved in a signal transduction pathway controlling epididymal function and male fertility.,PTM:Proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit .,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,subunit:Forms a heterodimer, consisting of a large extracellular region linked to a seven-transmembrane moiety.,tissue specificity:Epididymis specific. Both subunits were associated with apical membranes of efferent ductule and proximal epididymal duct epithelia.,
