Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Protein name
G-protein coupled receptor 3 (ACCA orphan receptor)
Immunogen
Synthesized peptide derived from human protein . at AA range: 260-340
Specificity
GPR3 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease. [provided by RefSeq, Oct 2012],
Function
function:Orphan receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed predominantly in the central nervous system, and at low levels in the lung, kidney, testis, ovary and eye.,
