Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
G-protein coupled receptor 161 (G-protein coupled receptor RE2)
Immunogen
Synthesized peptide derived from human protein . at AA range: 180-260
Specificity
GP161 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (Matteson et al., 2008 [PubMed 18250320]).[supplied by OMIM, Aug 2008],
Function
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,
