Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Protein name
Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor)
Immunogen
Synthesized peptide derived from human protein . at AA range: 40-120
Specificity
CALRL Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 2 family.,subunit:Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.,tissue specificity:Predominantly expressed in the lung and heart.,
Function
function:Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 2 family.,subunit:Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.,tissue specificity:Predominantly expressed in the lung and heart.,