Reactive species
Human;Rat;Mouse
Antibody type
Polyclonal Antibody
Protein name
Endothelin-2 (ET-2) (Preproendothelin-2) (PPET2)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
EDN2 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014],
Function
function:Endothelins are endothelium-derived vasoconstrictor peptides.,similarity:Belongs to the endothelin/sarafotoxin family.,tissue specificity:Expressed in lung, but not in placental stem villi vessels or cultured placental villi smooth muscle cells.,
