Reactive species
Human;Rat;Mouse
Antibody type
Polyclonal Antibody
Gene Name
KREMEN1 KREMEN KRM1
Protein name
Kremen protein 1 (Dickkopf receptor) (Kringle domain-containing transmembrane protein 1) (Kringle-containing protein marking the eye and the nose)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
KREM1 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008],
Function
function:Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling.,similarity:Contains 1 CUB domain.,similarity:Contains 1 kringle domain.,similarity:Contains 1 WSC domain.,
