Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Gene Name
SLITRK5 KIAA0918 LRRC11
Protein name
SLIT and NTRK-like protein 5 (Leucine-rich repeat-containing protein 11)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SLIK5 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM, Mar 2008],
Function
function:Suppresses neurite outgrowth.,similarity:Belongs to the SLITRK family.,similarity:Contains 16 LRR (leucine-rich) repeats.,tissue specificity:Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla.,
