Reactive species
Human;Rat;Mouse
Antibody type
Polyclonal Antibody
Protein name
Down syndrome cell adhesion molecule (CHD2)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
DSCAM Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs), and is involved in human central and peripheral nervous system development. This gene is a candidate for Down syndrome and congenital heart disease (DSCHD). A gene encoding a similar Ig-CAM protein is located on chromosome 11. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012],
Function
function:Cell adhesion molecule that can mediate cation-independent homophilic binding activity. Could be involved in nervous system development.,similarity:Contains 10 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 6 fibronectin type-III domains.,tissue specificity:Primarily expressed in brain.,
