Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Protein name
Ras and EF-hand domain-containing protein (Ras-related protein Rab-45)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
RASEF Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene. [provided by RefSeq, Nov 2012],
Function
function:Binds predominantly GDP, and also GTP.,similarity:Belongs to the small GTPase superfamily. Rab family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer.,tissue specificity:Down-regulated in cutaneous melanoma cells but not in breast cancer cells.,
