Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
Disrupted in renal carcinoma protein 1 (Disrupted in renal cancer protein)
Immunogen
Synthesized peptide derived from human protein . at AA range: 20-100
Specificity
DIRC1 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene consists of two exons and encodes a 104aa protein. Disruption of this gene by translocation t(2;3)(q33;q21) is associated with familial clear cell renal cancer. [provided by RefSeq, Sep 2010],
Function
disease:A chromosomal aberration involving DIRC1 is found in familial renal cell carcinoma 1-related translocation t(2;3)(q33;q21) (RCC1).,tissue specificity:Expressed at low steady-state level in adult placenta, testis, ovary, prostate, fetal kidney, spleen and skeletal muscle.,
