Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
AMY-1-associating protein expressed in testis 1 (AAT-1)
Immunogen
Synthesized peptide derived from human protein . at AA range: 310-390
Specificity
AAT1 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
alternative products:Additional isoforms (AAT-1L and AAT-1S) may exist,function:Isoform 4 may play a role in spermatogenesis.,PTM:Isoform 4 is phosphorylated by PKA.,subcellular location:Isoform 4 is found in the mitochondria and localized in the neck of the sperm.,subunit:Interacts with AMY1 and AKAP1. Isoform 4 belongs to a complex together with AMY1, AKAP1 and PRKAR2B. Isoform 3 does not interact with AMY1.,tissue specificity:Isoform 1 is strongly expressed in the liver. Isoform 4 is widely expressed, but strongly expressed in all spermatogenesis-related tissues, including the testis, the epithelium of cauda and the corpus epididymis. Isoform 4 is present in the spermatid and mature sperm. Isoform 4 is also expressed in Leydig cells. Isoform 3 is expressed in the testis.,
Function
alternative products:Additional isoforms (AAT-1L and AAT-1S) may exist,function:Isoform 4 may play a role in spermatogenesis.,PTM:Isoform 4 is phosphorylated by PKA.,subcellular location:Isoform 4 is found in the mitochondria and localized in the neck of the sperm.,subunit:Interacts with AMY1 and AKAP1. Isoform 4 belongs to a complex together with AMY1, AKAP1 and PRKAR2B. Isoform 3 does not interact with AMY1.,tissue specificity:Isoform 1 is strongly expressed in the liver. Isoform 4 is widely expressed, but strongly expressed in all spermatogenesis-related tissues, including the testis, the epithelium of cauda and the corpus epididymis. Isoform 4 is present in the spermatid and mature sperm. Isoform 4 is also expressed in Leydig cells. Isoform 3 is expressed in the testis.,
