Reactive species
Human;Mouse;Rat
Applications
WB;IHC;IF;ELISA
Protein name
Pituitary tumor-transforming gene 1 protein-interacting protein
Immunogen
The antiserum was produced against synthesized peptide derived from human PTTG. AA range:116-165
Specificity
PBF Polyclonal Antibody detects endogenous levels of PBF protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
PTTG1IP; C21orf1; C21orf3; Pituitary tumor-transforming gene 1 protein-interacting protein; Pituitary tumor-transforming gene protein-binding factor; PBF; PTTG-binding factor
Background
This gene encodes a single-pass type I integral membrane protein, which binds to pituitary tumor-transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013],
Function
function:May facilitate PTTG1 nuclear translocation.,induction:By transcription factor RUNX2.,subcellular location:According to PubMed:10781616 it is found in the cytoplasm and the nucleus.,subunit:Interacts with PTTG1.,tissue specificity:Ubiquitous.,
