Reactive species
Human;Rat;Mouse;
Applications
IHC;IF;ELISA
Protein name
p53-regulated apoptosis-inducing protein 1
Immunogen
The antiserum was produced against synthesized peptide derived from human TPIP1. AA range:75-124
Specificity
p53AIP1 Polyclonal Antibody detects endogenous levels of p53AIP1 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
TP53AIP1; p53-regulated apoptosis-inducing protein 1; p53AIP1
Background
This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011],
Function
function:May play an important role in mediating p53/TP53-dependent apoptosis.,induction:By p53/TP53.,tissue specificity:Only found to be expressed in thymus.,
